HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: GBB2 (P62879)
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (G protein subunit beta-2) (Transducin beta chain 2)
Gene: GNB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 340
+	Hs
		921784 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		919704 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		849304 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		895772 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		GBB2_HUMAN (1-340): 2.89e-111: 328: 100.00
+	Hs
		908309 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		GBB1_HUMAN (1-340): 1.35e-106: 316: 90.29
+	Hs
		908940 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SNR40_HUMAN (130-340): 6.93e-58: 192: 23.36
+	Hs
		903084 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR5_HUMAN (263-340): 9.69e-19: 87.4: 26.92
+	Hs
		196986 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		PRP4_HUMAN (51-253): 4.41e-11: 65.9: 24.88