HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: ULA1 (Q13564)
NEDD8-activating enzyme E1 regulatory subunit (Amyloid beta precursor protein-binding protein 1, 59 kDa) (APP-BP1) (Amyloid protein-binding protein 1) (Proto-oncogene protein 1)
Gene: NAE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ThiF~UQ_con
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Hs			1 534
+	Hs
		919796 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		UBA3_HUMAN (22-369): 1.13e-79: 258: 16.62
+	Hs
		909266 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SAE1_HUMAN (6-265): 2.25e-73: 238: 24.03
+	Hs
		607190 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607050 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607026 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607039 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		782203 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		UBA7_HUMAN (4-315): 9.42e-60: 215: 18.77
+	Hs
		607129 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607136 UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607023 UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607028 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607047 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		607054 UBE2B_HUMAN (4-149): 8e-64: 195: 30.67		UBA1_HUMAN (1-384): 5.4e-56: 204: 20.61
+	Hs
		48107 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		UBA6_HUMAN (1-373): 4.77e-48: 181: 18.54
+	Hs
		48104 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		UBA6_HUMAN (1-373): 4.77e-48: 181: 18.54
+	Hs
		48106 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		UBA6_HUMAN (1-373): 4.77e-48: 181: 18.54
+	Sc
		549788 UBC4_YEAST (1-149): 7.24e-71: 212: 32.03		UBA1_YEAST (3-388): 4.13e-45: 172: 16.24
+	Sp
		293848 UBC4_SCHPO (7-149): 2.5e-70: 211: 29.25		UBA1_SCHPO (8-388): 4.21e-41: 160: 17.80
+	Sp
		293850 UBC8_SCHPO (1-178): 2.41e-62: 192: 55.31		UBA1_SCHPO (8-388): 4.21e-41: 160: 17.80
+	Dm
		715098 UBE2N_DROME (5-152): 6.43e-62: 190: 34.21		Q8T0L3_DROME (2-366): 1.67e-40: 158: 18.83