HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 334
+	Sc
		549819 UBC4_YEAST (1-149): 7.24e-71: 212: 32.03		RPN11_YEAST (39-333): 9.57e-75: 234: 29.14
+	Hs
		130834 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		PSDE_HUMAN (50-331): 1.67e-79: 246: 31.51
+	Hs
		176990 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		EIF3H_HUMAN (52-320): 2.17e-66: 214: 18.57
+	Hs
		849178 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		PSMD7_HUMAN (52-325): 1.07e-66: 214: 14.79
+	Hs
		124799 UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		124821 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		EIF3F_HUMAN (44-328): 3.25e-64: 208: 14.48
+	Hs
		805515 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		BRCC3_HUMAN (56-203): 4.61e-43: 152: 21.23
+	Hs
		805519 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		BRCC3_HUMAN (56-203): 4.61e-43: 152: 21.23