HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: OTUB1 (Q96FW1)
Ubiquitin thioesterase OTUB1 (EC 3.4.19.12) (Deubiquitinating enzyme OTUB1) (OTU domain-containing ubiquitin aldehyde-binding protein 1) (Otubain-1) (hOTU1) (Ubiquitin-specific-processing protease OTUB1)
Gene: OTUB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38113892
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Peptidase_C65~UQ_con
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 271
+	Hs
		1291615 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		919824 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		849408 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		895878 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		1282326 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		1291545 UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Hs
		851868 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		OTUB1_HUMAN (1-271): 3.25e-150: 422: 100.00
+	Ce
		715115 UBC2_CAEEL (7-150): 2.02e-72: 216: 31.08		OTUBL_CAEEL (3-271): 2.76e-122: 352: 34.42