HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: WDR26 (Q9H7D7)
WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2)
Gene: WDR26

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	1.00	0.847

Property	Details
Experiments	29911972, 27173435, 38113892
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	UQ_con~WD40
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 661
+	Hs
		245581 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		245625 UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00		TBL1X_HUMAN (396-661): 8.44e-63: 220: 19.79
+	Hs
		895800 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		908636 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SMU1_HUMAN (477-661): 1.05e-44: 169: 17.41
+	Hs
		921784 UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		903084 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR5_HUMAN (186-512): 3.62e-45: 165: 15.18
+	Hs
		919704 UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		849304 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		895772 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		908310 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		GBB2_HUMAN (462-661): 1.61e-37: 144: 12.20
+	Hs
		909331 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		WDR3_HUMAN (538-660): 2.95e-20: 97.9: 17.89
+	Hs
		282872 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		CIAO1_HUMAN (359-641): 1.55e-15: 80.5: 26.18
+	Hs
		908940 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		SNR40_HUMAN (17-381): 1.88e-13: 74.4: 13.39
+	Sc
		634230 UBC8_YEAST (5-157): 4e-64: 198: 58.44		GID7_YEAST (279-419): 1.12e-10: 67: 26.49