HitPredict

Interactor 1: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	17588522, 38113892
Identification Methods	enzymatic study, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000209 - protein polyubiquitination GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 183 Hs			1 1215
+	Hs
		849473 UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		895937 UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		851900 UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1270382 UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		908905 UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02