HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: DEN2B (P78524)
DENN domain-containing protein 2B (HeLa tumor suppression 1) (Suppression of tumorigenicity 5 protein)
Gene: DENND2B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.580

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1137
+	Hs
		909741 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYCPP_HUMAN (590-1129): 2.1e-112: 388: 18.77
+	Hs
		909687 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DEN1B_HUMAN (692-1120): 2.86e-116: 380: 25.34
+	Hs
		909665 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DEN4C_HUMAN (573-1106): 3.05e-101: 355: 18.80
+	Hs
		309464 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MTMR5_HUMAN (693-1130): 2.42e-92: 328: 16.97
+	Hs
		909848 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DEN1A_HUMAN (702-1122): 1.19e-71: 261: 26.07