HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: CDK17 (Q00537)
Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)
Gene: CDK17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.635

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 523
+	Hs
		909448 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625306 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		909447 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98
+	Hs
		909472 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	Hs
		300632 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	At
		965298 14332_ARATH (4-255): 1.05e-147: 414: 74.41		MPK7_ARATH (161-519): 2.65e-138: 405: 30.06
+	Dm
		955007 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q7KM03_DROME (108-506): 5.01e-134: 400: 50.97
+	Dm
		955011 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q94888_DROME (87-506): 2.71e-134: 400: 48.50
+	Sc
		565487 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		PHO85_YEAST (191-475): 2.24e-129: 380: 50.51