HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: KIF23 (Q02241)
Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1)
Gene: KIF23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	31586073, 35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 960
+	Hs
		231490 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KIF1B_HUMAN (22-927): 1.18e-124: 418: 16.49
+	Hs
		910062 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KI13B_HUMAN (23-845): 2.95e-123: 414: 16.08
+	Dm
		54781 1433E_DROME (1-254): 2.95e-146: 411: 82.69		A1ZA18_DROME (215-463): 1.8e-32: 139: 38.74
+	Mm
		702835 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		KIF5A_MOUSE (18-147): 7.24e-19: 94.6: 32.33
+	Hs
		909493 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		KIF5A_HUMAN (18-147): 7.45e-19: 94.6: 32.33
+	Sc
		660042 BMH2_YEAST (4-242): 1.14e-134: 382: 77.08		KIP1_YEAST (12-446): 6.12e-31: 133: 27.70
+	Sc
		660035 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		KIP1_YEAST (12-446): 6.12e-31: 133: 27.70
+	Mm
		910349 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		KI21B_MOUSE (413-849): 6.3e-10: 65.7: 6.41