HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	35271311, 36931259, 17979178
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1591
+	Mm
		910228 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		ARG28_MOUSE (645-1544): 1.35e-118: 413: 13.84
+	Hs
		909803 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARG28_HUMAN (647-1544): 9.69e-115: 402: 13.10
+	Hs
		909491 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKP13_HUMAN (646-1590): 1.94e-104: 373: 13.83
+	Hs
		909883 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG2_HUMAN (821-1575): 9.12e-97: 338: 13.13
+	Hs
		909551 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG7_HUMAN (818-1568): 7.77e-97: 333: 14.38
+	Hs
		909921 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPT13_HUMAN (801-1473): 7.06e-90: 309: 17.13
+	Hs
		909717 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		FGD6_HUMAN (764-1451): 2.66e-80: 294: 16.11
+	Hs
		50576 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PKHG3_HUMAN (984-1587): 7.98e-80: 291: 17.03
+	Hs
		910068 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG4_HUMAN (992-1459): 3.98e-82: 287: 19.96