HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: RGPS2 (Q86X27)
Ras-specific guanine nucleotide-releasing factor RalGPS2 (Ral GEF with PH domain and SH3-binding motif 2) (RalA exchange factor RalGPS2)
Gene: RALGPS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 583
+	Hs
		910200 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RPGF2_HUMAN (18-474): 8.7e-102: 339: 17.58
+	Hs
		171544 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RGL2_HUMAN (26-480): 5.4e-102: 327: 20.83
+	Hs
		909851 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RPGF6_HUMAN (18-462): 3.55e-96: 323: 15.79
+	Sc
		389694 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		CDC25_YEAST (45-296): 1.36e-24: 111: 27.74