HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: NAV2 (Q8IVL1)
Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2)
Gene: NAV2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 2488
+	Hs
		909831 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NAV1_HUMAN (494-2488): 0: 618: 34.28
+	Mm
		910306 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NAV1_MOUSE (440-2488): 7.38e-178: 600: 34.20
+	Mm
		910291 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		FLNA_MOUSE (48-1900): 3.54e-116: 416: 10.62
+	Hs
		626091 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		APC_HUMAN (185-1830): 2.12e-70: 266: 10.50
+	Hs
		910159 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MACF1_HUMAN (31-192): 3.76e-51: 203: 21.82
+	Hs
		211554 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ACTN4_HUMAN (84-187): 4.26e-30: 132: 29.81