HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: ARG28 (Q8N1W1)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor)
Gene: ARHGEF28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1705
+	Mm
		910228 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		ARG28_MOUSE (1-1705): 0: 1165: 80.09
+	Hs
		909491 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		AKP13_HUMAN (1-814): 3.86e-122: 429: 17.82
+	Hs
		909883 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG2_HUMAN (615-1525): 1.22e-103: 358: 35.81
+	Hs
		909717 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		FGD6_HUMAN (289-1349): 1.08e-90: 327: 13.66
+	Hs
		909933 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ALS2_HUMAN (335-1261): 1.6e-79: 293: 13.19
+	Hs
		910068 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ARHG4_HUMAN (815-1275): 1.7e-76: 271: 15.32
+	Hs
		909921 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SPT13_HUMAN (634-1221): 9.84e-74: 262: 13.55
+	Hs
		506563 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		BCR_HUMAN (401-1283): 7.4e-70: 260: 13.08
+	Sp
		788722 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		RGF1_SCHPO (411-1199): 8.04e-77: 283: 13.15