HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	31980649, 35271311, 36931259, 28514442, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 622
+	Hs
		909498 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		663970 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		910025 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		910185 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		505612 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		204644 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		640229 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Mm
		910287 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		FRM4A_MOUSE (12-334): 6.2e-85: 288: 19.64
+	Mm
		910323 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		909595 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75