HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: TSSK2 (Q96PF2)
Testis-specific serine/threonine-protein kinase 2 (TSK-2) (TSK2) (TSSK-2) (Testis-specific kinase 2) (EC 2.7.11.1) (DiGeorge syndrome protein G) (DGS-G) (Serine/threonine-protein kinase 22B)
Gene: TSSK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0035556 - intracellular signal transduction
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 358
+	Hs
		909980 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		TSSK1_HUMAN (1-336): 8.66e-147: 420: 67.61
+	At
		965360 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CIPKC_ARATH (2-333): 3.57e-135: 395: 31.05
+	At
		788672 14333_ARATH (1-253): 3.45e-147: 413: 74.12		CIPKC_ARATH (2-333): 3.57e-135: 395: 31.05
+	At
		1280891 14337_ARATH (2-255): 7.73e-147: 412: 71.21		CIPKC_ARATH (2-333): 3.57e-135: 395: 31.05
+	At
		965291 14332_ARATH (4-255): 1.05e-147: 414: 74.41		CDPK1_ARATH (4-355): 2.54e-131: 390: 24.38
+	At
		802001 14334_ARATH (4-255): 2.51e-145: 408: 73.62		CDPK1_ARATH (4-355): 2.54e-131: 390: 24.38
+	Hs
		883214 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK1_HUMAN (7-283): 1.97e-119: 364: 40.50
+	At
		788694 14335_ARATH (2-255): 3.04e-141: 398: 68.75		CDPK1_ARATH (4-355): 2.54e-131: 390: 24.38
+	Sc
		419854 BMH2_YEAST (4-242): 1.14e-134: 382: 77.08		SNF1_YEAST (8-356): 4.93e-126: 377: 30.95
+	Sc
		419824 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		SNF1_YEAST (8-356): 4.93e-126: 377: 30.95
+	Hs
		910013 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK2_HUMAN (12-272): 8.36e-52: 186: 39.85
+	Hs
		910187 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK3_HUMAN (12-273): 3.37e-51: 185: 37.88
+	Hs
		909916 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK4_HUMAN (18-272): 1.8e-51: 184: 39.15
+	Mm
		910231 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK3_MOUSE (18-272): 2.05e-51: 184: 40.39
+	Mm
		910308 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK4_MOUSE (18-272): 2.03e-51: 184: 39.15
+	Hs
		647862 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK3_HUMAN (18-272): 2.86e-51: 183: 39.92
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (18-272): 5.69e-51: 183: 38.52
+	Xl
		223344 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q804T2_XENLA (18-272): 6.32e-52: 185: 40.39
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (18-272): 4.75e-51: 183: 38.91