HitPredict

Interactor 1: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 37207277
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 255 Hs			1 1343
+	Mm
		99940 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		909664 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		DAB2P_HUMAN (97-1342): 0: 779: 46.78
+	Hs
		910133 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		909576 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		GAPD1_HUMAN (412-1051): 3.01e-122: 417: 13.70
+	Hs
		909774 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RASL3_HUMAN (182-865): 4.68e-111: 376: 35.91
+	Sp
		144985 RAD24_SCHPO (2-255): 7.25e-135: 382: 70.77		IQG1_SCHPO (135-691): 3.08e-105: 368: 14.08
+	Hs
		598455 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Mm
		910233 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NF1_MOUSE (408-712): 4.15e-82: 300: 23.51