Interactor 1: PIEZ1 (E2JF22)
Piezo-type mechanosensitive ion channel component 1 (Protein FAM38A)
Gene: Piezo1

Interactor 2: PIEZ1 (E2JF22)
Piezo-type mechanosensitive ion channel component 1 (Protein FAM38A)
Gene: Piezo1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.897

The method score is based on:

Property Details
Experiments 22343900, 26390154, 29261642, 29469092
Identification Methods comigration in non denaturing gel electrophoresis, cross-linking study, molecular sieving, x-ray crystallography, transmission electron microscopy, 3D electron microscopy
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PIEZO~PIEZO, PIEZO~Piezo_RRas_bdg, Piezo_RRas_bdg~Piezo_RRas_bdg
Common GO terms GO:0005261 - monoatomic cation channel activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
GO:0006812 - monoatomic cation transport
and 10 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 2547
Mm

1 2547
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024