HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: MARK4 (Q8CIP4)
MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)
Gene: MARK4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 255 Mm			1 752
+	Hs
		909916 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK4_HUMAN (1-752): 0: 719: 97.61
+	Hs
		647862 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK3_HUMAN (1-752): 0: 671: 60.37
+	Mm
		910231 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK3_MOUSE (1-752): 0: 671: 58.69
+	Xl
		223344 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q804T2_XENLA (1-752): 0: 672: 59.18
+	Mm
		910234 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK2_MOUSE (2-752): 0: 615: 48.62
+	Xl
		223345 O57468_XENLA (1-255): 1.7e-152: 426: 96.47		Q8QGV3_XENLA (1-752): 0: 618: 49.75
+	Hs
		909730 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK2_HUMAN (2-752): 0: 608: 48.07
+	Hs
		910106 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MARK1_HUMAN (1-752): 0: 604: 50.93
+	Mm
		910318 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		MARK1_MOUSE (1-752): 0: 604: 51.30
+	Dm
		90534 1433E_DROME (1-254): 2.95e-146: 411: 82.69		E1JGN0_DROME (3-752): 0: 576: 44.49
+	Hs
		909567 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MELK_HUMAN (59-752): 8.36e-168: 500: 27.40
+	Mm
		910272 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		BRSK2_MOUSE (55-504): 4.53e-150: 457: 36.85
+	Hs
		909786 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		BRSK2_HUMAN (55-504): 8.32e-150: 456: 36.85
+	Hs
		910187 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK3_HUMAN (39-596): 2.27e-141: 450: 36.98
+	Hs
		910071 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SNRK_HUMAN (54-748): 8.27e-145: 444: 25.21
+	Hs
		883214 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK1_HUMAN (37-653): 3.66e-141: 435: 33.02
+	Rn
		871214 1433E_RAT (1-255): 4.87e-154: 430: 100.00		AAPK1_RAT (29-570): 1.2e-139: 424: 27.93
+	Sc
		419854 BMH2_YEAST (4-242): 1.14e-134: 382: 77.08		SNF1_YEAST (44-473): 7.73e-141: 429: 34.36
+	Sc
		419824 BMH1_YEAST (2-243): 2.43e-134: 381: 75.72		SNF1_YEAST (44-473): 7.73e-141: 429: 34.36
+	Hs
		910013 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		SIK2_HUMAN (56-367): 2.08e-104: 342: 55.17