HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0021766 - hippocampus development GO:0021987 - cerebral cortex development
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 1161
+	Hs
		909871 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		909755 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		PHLB1_HUMAN (281-916): 3.43e-37: 154: 14.88
+	Hs
		909658 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Mm
		93548 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		DESP_MOUSE (706-1133): 3.64e-15: 83.3: 12.56
+	Zm
		5465 B6U284_MAIZE (3-255): 8.23e-147: 412: 70.59		A0A1D6DZK4_MAIZE (684-1161): 9.86e-17: 88.3: 9.21
+	Hs
		728460 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH11_HUMAN (796-1161): 5.47e-11: 69.5: 12.30
+	Hs
		725130 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		MYH10_HUMAN (617-910): 9.54e-10: 65.3: 13.27
+	Hs
		909488 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		CGNL1_HUMAN (722-989): 7.46e-09: 62.5: 21.07
+	Dm
		955019 1433E_DROME (1-254): 2.95e-146: 411: 82.69		Q9VCC9_DROME (779-1108): 3.26e-09: 63.3: 9.67