HitPredict

Interactor 1: 1433E (P62259)
14-3-3 protein epsilon (14-3-3E)
Gene: Ywhae

Interactor 2: RIMS2 (Q9EQZ7)
Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 2)
Gene: RIMS2

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16944949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0019904 - protein domain specific binding GO:0044325 - transmembrane transporter binding GO:0044877 - protein-containing complex binding GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 255 Mm			1 1530
+	Rn
		910361 1433E_RAT (1-255): 4.87e-154: 430: 100.00		RIMS1_RAT (194-1530): 1.02e-60: 232: 29.93
+	Hs
		135774 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		P3C2B_HUMAN (747-947): 3.14e-41: 168: 22.22
+	Hs
		909930 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		NED4L_HUMAN (1378-1490): 3.33e-25: 116: 25.42
+	Mm
		910302 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NED4L_MOUSE (1387-1490): 8.53e-25: 114: 25.47
+	Mm
		910280 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		RIMS3_MOUSE (693-944): 3e-16: 83.4: 17.56
+	Hs
		909754 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		RIMS1_HUMAN (956-1505): 7.04e-15: 82.8: 12.07
+	Mm
		808343 1433E_MOUSE (1-255): 4.87e-154: 430: 100.00		NEDD4_MOUSE (1335-1489): 1.44e-14: 81.3: 22.29
+	Rn
		910358 1433E_RAT (1-255): 4.87e-154: 430: 100.00		NEDD4_RAT (1335-1489): 4.78e-14: 79.7: 22.29
+	Hs
		128836 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		P3C2A_HUMAN (819-939): 5.6e-11: 69.7: 34.43
+	Hs
		909970 1433E_HUMAN (1-255): 4.87e-154: 430: 100.00		ESYT1_HUMAN (816-939): 5.03e-10: 66.6: 32.54