HitPredict

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: RUXG (P62308)
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)
Gene: SNRPG

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 28514442, 32296183, 9417867, 33961781, 30021884, 34349018, 35235311, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~LSM
Common GO terms GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 20 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 92
Hs

1 76
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ At
+ Ce
+ Dm
+ Ce
+ Hs
+ At
+ At
+ At
+ At
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024