HitPredict

Interactor 1: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Interactor 2: LSM10 (Q969L4)
U7 snRNA-associated Sm-like protein LSm10
Gene: LSM10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0005654 - nucleoplasm GO:0005683 - U7 snRNP
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 92 Hs			1 123
+	Hs
		911779 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		LSM4_HUMAN (18-90): 3.27e-32: 111: 27.03
+	Hs
		911609 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Hs
		911611 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		SMD3_HUMAN (18-114): 3.72e-31: 108: 20.62
+	Hs
		911773 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		LSM2_HUMAN (19-102): 7.92e-31: 107: 25.58
+	Dm
		218372 RUXE_DROME (1-91): 4.83e-45: 141: 75.82		SMD3_DROME (18-113): 4.72e-31: 109: 20.83
+	Hs
		911605 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		RUXF_HUMAN (20-83): 3.98e-26: 95: 26.56
+	Hs
		911608 RUXE_HUMAN (1-92): 2.95e-48: 149: 100.00		LSM6_HUMAN (6-82): 3.34e-25: 92.3: 27.27
+	At
		1227147 Q8LAK5_ARATH (9-89): 8.38e-41: 130: 69.14		RUXF_ARATH (20-96): 8.07e-28: 99.3: 23.08
+	At
		1352881 Q9ZV45_ARATH (9-89): 1.5e-40: 130: 67.90		RUXF_ARATH (20-96): 8.07e-28: 99.3: 23.08
+	Sc
		795435 RUXE_YEAST (12-89): 4.26e-36: 119: 49.41		SMD3_YEAST (18-104): 1.11e-27: 99.3: 20.69
+	Sc
		746366 RUXE_YEAST (12-89): 4.26e-36: 119: 49.41		LSM2_YEAST (19-101): 1.96e-25: 93.5: 21.18
+	Sc
		970253 RUXE_YEAST (12-89): 4.26e-36: 119: 49.41		SMD1_YEAST (17-107): 1.32e-23: 90.5: 20.34