HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: SART3 (Q15020)
Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)
Gene: SART3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	33961781, 28514442, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~Lsm_interact
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 86 Hs			1 963
+	Hs
		1063317 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SART3_HUMAN (1-963): 0: 638: 100.00
+	Hs
		912227 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		SART3_HUMAN (1-963): 0: 638: 100.00
+	Hs
		1063313 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SART3_HUMAN (1-963): 0: 638: 100.00
+	Ce
		1088927 Q95XN6_CAEEL (1-74): 8.43e-31: 104: 51.35		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Ce
		712466 RUXF_CAEEL (4-82): 3.26e-30: 103: 70.89		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Ce
		1088921 LSM4_CAEEL (7-80): 1.03e-28: 101: 28.00		SART3_CAEEL (73-962): 3.23e-124: 399: 24.26
+	Hs
		911958 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35
+	Hs
		1318167 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		CRNL1_HUMAN (36-683): 9.67e-110: 360: 14.35
+	Hs
		300299 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300099 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300102 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Hs
		300294 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10
+	Sc
		795434 SMD3_YEAST (1-76): 1.44e-26: 95: 25.00		CLF1_YEAST (48-658): 1.77e-74: 260: 13.68
+	Sc
		873679 RUXF_YEAST (4-77): 6.37e-26: 93: 56.00		CLF1_YEAST (48-658): 1.77e-74: 260: 13.68
+	Sc
		763234 SMD3_YEAST (1-76): 1.44e-26: 95: 25.00		PRP39_YEAST (130-596): 1.57e-67: 239: 13.25
+	Sc
		763240 RUXF_YEAST (4-77): 6.37e-26: 93: 56.00		PRP39_YEAST (130-596): 1.57e-67: 239: 13.25
+	Dm
		1369701 Q9VKW8_DROME (7-80): 4.66e-33: 113: 32.00		RNP4F_DROME (791-895): 5.63e-16: 85.1: 40.00
+	Hs
		911970 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SYF1_HUMAN (34-365): 2.09e-14: 79.7: 12.39
+	Dm
		1376453 Q9W2P5_DROME (1-79): 2.76e-29: 101: 44.30		RNP4F_DROME (791-895): 5.63e-16: 85.1: 40.00
+	Sp
		223541 RUXF_SCHPO (3-74): 9.06e-29: 99: 66.67		PRP1_SCHPO (35-363): 5.2e-15: 82: 11.64