HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: SMN (Q16637)
Survival motor neuron protein (Component of gems 1) (Gemin-1)
Gene: SMN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	28514442, 33961781, 35271311, 24981860, 10556282, 19928837, 21816274
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol and 1 others more... GO:0034719 - SMN-Sm protein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 86 Hs			1 294
+	Hs
		1084949 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		912231 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		1084943 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Hs
		912650 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SMN_HUMAN (1-294): 5.52e-150: 423: 100.00
+	Dm
		218378 SMD3_DROME (5-76): 1.75e-19: 78.4: 19.44		SMN_DROME (27-179): 9.4e-54: 176: 24.68
+	Hs
		278923 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SPF30_HUMAN (44-158): 1.19e-31: 119: 32.17