HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: SMU1 (Q2TAY7)
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]
Gene: SMU1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing GO:0071005 - U2-type precatalytic spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 86 Hs			1 513
+	Hs
		1103034 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SMU1_HUMAN (1-513): 7.53e-153: 447: 100.00
+	Hs
		911966 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		WDR26_HUMAN (3-513): 2.59e-99: 314: 19.45
+	Hs
		903646 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903090 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903627 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		903093 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		WDR5_HUMAN (78-425): 2.83e-76: 245: 21.25
+	Hs
		1288409 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		911927 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		1288404 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50
+	Hs
		912701 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SNR40_HUMAN (18-240): 3.64e-24: 105: 10.50