HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: WDR83 (Q9BRX9)
WD repeat domain-containing protein 83 (Mitogen-activated protein kinase organizer 1) (MAPK organizer 1)
Gene: WDR83

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005681 - spliceosomal complex GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 86 Hs			1 315
+	Hs
		209418 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		912719 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		WDR83_HUMAN (1-315): 2.96e-102: 303: 100.00
+	Hs
		236204 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		209501 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		PLRG1_HUMAN (2-312): 1.61e-88: 275: 23.15
+	Hs
		236268 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		236206 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		PRP17_HUMAN (8-304): 1.94e-87: 274: 23.40
+	Hs
		1288409 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		911927 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903646 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		903090 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Hs
		912695 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		FBXW7_HUMAN (103-315): 7.36e-58: 199: 23.61
+	Hs
		1288404 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		912701 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SNR40_HUMAN (101-312): 1.44e-55: 185: 18.47
+	Hs
		903627 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Dm
		218374 SMD3_DROME (5-76): 1.75e-19: 78.4: 19.44		Q9VPL0_DROME (2-217): 1.78e-56: 187: 20.26
+	Hs
		903093 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		WDR5_HUMAN (140-312): 2.71e-53: 178: 23.60
+	Sp
		195146 RUXF_SCHPO (3-74): 9.06e-29: 99: 66.67		PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47
+	Sp
		195204 SMD3_SCHPO (8-76): 1.62e-23: 87.3: 23.19		PRP17_SCHPO (224-306): 1.02e-11: 67.5: 16.47