HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: SYF1 (Q9HCS7)
Pre-mRNA-splicing factor SYF1 (Protein HCNP) (XPA-binding protein 2)
Gene: XAB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0071007 - U2-type catalytic step 2 spliceosome GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 86 Hs			1 855
+	Hs
		912738 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SYF1_HUMAN (1-855): 0: 602: 100.00
+	Sc
		795418 SMD3_YEAST (1-76): 1.44e-26: 95: 25.00		SYF1_YEAST (19-733): 1.86e-87: 298: 22.31
+	Sc
		873663 RUXF_YEAST (4-77): 6.37e-26: 93: 56.00		SYF1_YEAST (19-733): 1.86e-87: 298: 22.31
+	Hs
		911958 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		911872 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		CTR9_HUMAN (44-847): 4.01e-41: 165: 10.93
+	Hs
		1318167 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		CRNL1_HUMAN (166-822): 5.62e-47: 182: 14.51
+	Hs
		1063317 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		911838 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		912227 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		300299 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		300099 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		1063313 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		300102 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		912638 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SART3_HUMAN (18-578): 1.7e-31: 134: 12.80
+	Hs
		300294 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Hs
		300104 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		PRP6_HUMAN (2-353): 4.69e-26: 117: 12.92
+	Sp
		223541 RUXF_SCHPO (3-74): 9.06e-29: 99: 66.67		PRP1_SCHPO (3-435): 4.99e-19: 94.7: 13.66
+	Sp
		1015547 SMD3_SCHPO (8-76): 1.62e-23: 87.3: 23.19		PRP1_SCHPO (3-435): 4.99e-19: 94.7: 13.66
+	Sc
		795434 SMD3_YEAST (1-76): 1.44e-26: 95: 25.00		CLF1_YEAST (3-250): 5.35e-11: 68.5: 12.06
+	Sc
		873679 RUXF_YEAST (4-77): 6.37e-26: 93: 56.00		CLF1_YEAST (3-250): 5.35e-11: 68.5: 12.06