HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: DDX20 (Q9UHI6)
Probable ATP-dependent RNA helicase DDX20 (EC 3.6.1.15) (EC 3.6.4.13) (Component of gems 3) (DEAD box protein 20) (DEAD box protein DP 103) (Gemin-3)
Gene: DDX20

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.724

Property	Details
Experiments	24981860, 10601333, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0034719 - SMN-Sm protein complex
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 86 Hs			1 824
+	Hs
		1355475 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		DDX20_HUMAN (1-824): 0: 727: 100.00
+	Hs
		1355472 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		DDX20_HUMAN (1-824): 0: 727: 100.00
+	Hs
		912750 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		DDX20_HUMAN (1-824): 0: 727: 100.00
+	Hs
		640677 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		DDX6_HUMAN (25-444): 7.61e-164: 486: 32.62
+	Sc
		746288 LSM2_YEAST (9-86): 4.37e-21: 81.1: 29.63		DHH1_YEAST (37-450): 3.88e-165: 490: 35.73
+	Sc
		761950 LSM4_YEAST (7-85): 1.93e-19: 79.2: 23.33		DHH1_YEAST (37-450): 3.88e-165: 490: 35.73
+	Sc
		762028 LSM6_YEAST (9-76): 1.65e-19: 76.6: 34.72		DHH1_YEAST (37-450): 3.88e-165: 490: 35.73
+	Sc
		762005 LSM3_YEAST (5-82): 2.63e-09: 50.7: 23.53		DHH1_YEAST (37-450): 3.88e-165: 490: 35.73
+	Hs
		911887 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		DDX42_HUMAN (9-756): 3.7e-132: 418: 17.75
+	Hs
		571387 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		DDX5_HUMAN (13-488): 1.13e-131: 407: 22.70
+	Hs
		757540 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		IF4A3_HUMAN (38-444): 2.03e-124: 381: 32.84
+	Hs
		757543 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		IF4A3_HUMAN (38-444): 2.03e-124: 381: 32.84
+	Hs
		911833 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		DX39B_HUMAN (64-440): 3.19e-67: 231: 36.05