HitPredict

Interactor 1: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Interactor 2: STRAP (Q9Y3F4)
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)
Gene: STRAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0034719 - SMN-Sm protein complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 86 Hs			1 350
+	Hs
		912760 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		STRAP_HUMAN (1-350): 2.21e-84: 261: 100.00
+	Dm
		218374 SMD3_DROME (5-76): 1.75e-19: 78.4: 19.44		Q9VPL0_DROME (1-208): 3.69e-48: 167: 19.64
+	Hs
		1288409 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		911927 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		1288404 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		903646 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		903090 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		912701 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		1103034 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Hs
		197113 LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		911856 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Hs
		196988 RUXF_HUMAN (1-75): 6.7e-33: 110: 100.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		912695 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		196991 LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		903627 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		903093 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		197110 LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		196993 SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47