HitPredict

Interactor 1: SMD1 (P62314)
Small nuclear ribonucleoprotein Sm D1 (Sm-D1) (Sm-D autoantigen) (snRNP core protein D1)
Gene: SNRPD1

Interactor 2: SRPK3 (Q9UPE1)
SRSF protein kinase 3 (EC 2.7.11.1) (Muscle-specific serine kinase 1) (MSSK-1) (Serine/arginine-rich protein-specific kinase 3) (SR-protein-specific kinase 3) (Serine/threonine-protein kinase 23)
Gene: SRPK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23602568
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000245 - spliceosomal complex assembly GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 119 Hs			1 567
+	Hs
		911998 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SRPK3_HUMAN (27-567): 5.16e-140: 418: 100.00
+	Hs
		912266 SMD1_HUMAN (1-96): 1.18e-34: 117: 100.00		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		625313 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		CDK2_HUMAN (274-566): 4.84e-82: 260: 17.97
+	Dm
		247461 Q9VTW6_DROME (1-88): 7.09e-34: 114: 31.11		MK38B_DROME (74-371): 3.7e-71: 234: 17.32
+	Hs
		911803 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SRPK2_HUMAN (297-566): 8.12e-72: 244: 57.69
+	Hs
		912711 SMD3_HUMAN (2-102): 1.06e-31: 110: 28.71		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Dm
		248418 Q9VTW6_DROME (1-88): 7.09e-34: 114: 31.11		MK38A_DROME (74-296): 6.1e-57: 196: 18.62
+	Hs
		911940 RUXF_HUMAN (3-69): 8.6e-27: 96.6: 28.36		SRPK1_HUMAN (368-566): 2.74e-59: 210: 67.84
+	Dm
		218364 SMD3_DROME (2-102): 6.25e-32: 111: 24.75		DYRK2_DROME (37-258): 2.9e-53: 194: 23.77