HitPredict

Interactor 1: SMD3 (P62318)
Small nuclear ribonucleoprotein Sm D3 (Sm-D3) (snRNP core protein D3)
Gene: SNRPD3

Interactor 2: STRAP (Q9Y3F4)
Serine-threonine kinase receptor-associated protein (MAP activator with WD repeats) (UNR-interacting protein) (WD-40 repeat protein PT-WD)
Gene: STRAP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15848170
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0034719 - SMN-Sm protein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 350
+	Hs
		912005 RUXF_HUMAN (1-72): 4.64e-28: 100: 24.66		STRAP_HUMAN (1-350): 2.21e-84: 261: 100.00
+	Dm
		218374 SMD3_DROME (1-107): 1.78e-37: 125: 83.18		Q9VPL0_DROME (1-208): 3.69e-48: 167: 19.64
+	Hs
		912701 SMD3_HUMAN (1-126): 1.77e-42: 137: 100.00		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		912695 SMD3_HUMAN (1-126): 1.77e-42: 137: 100.00		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		1288409 LSM4_HUMAN (5-84): 8.75e-35: 118: 30.86		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		912352 SMD1_HUMAN (7-94): 9.52e-33: 112: 27.27		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		903093 SMD3_HUMAN (1-126): 1.77e-42: 137: 100.00		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		1288404 LSM2_HUMAN (8-91): 1.44e-30: 106: 22.09		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		912348 SMD1_HUMAN (7-94): 9.52e-33: 112: 27.27		FBXW7_HUMAN (209-344): 2.04e-24: 106: 15.94
+	Hs
		196993 SMD3_HUMAN (1-126): 1.77e-42: 137: 100.00		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		911927 RUXF_HUMAN (1-72): 4.64e-28: 100: 24.66		SNR40_HUMAN (1-126): 8.45e-28: 113: 22.96
+	Hs
		903646 LSM4_HUMAN (5-84): 8.75e-35: 118: 30.86		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		1103034 LSM4_HUMAN (5-84): 8.75e-35: 118: 30.86		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Hs
		903091 SMD1_HUMAN (7-94): 9.52e-33: 112: 27.27		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		197113 LSM4_HUMAN (5-84): 8.75e-35: 118: 30.86		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		903627 LSM2_HUMAN (8-91): 1.44e-30: 106: 22.09		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		903090 RUXF_HUMAN (1-72): 4.64e-28: 100: 24.66		WDR5_HUMAN (253-346): 5.02e-18: 85.4: 18.09
+	Hs
		197110 LSM2_HUMAN (8-91): 1.44e-30: 106: 22.09		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47
+	Hs
		911856 RUXF_HUMAN (1-72): 4.64e-28: 100: 24.66		SMU1_HUMAN (26-293): 7.19e-16: 80.5: 26.87
+	Hs
		196988 RUXF_HUMAN (1-72): 4.64e-28: 100: 24.66		PRP4_HUMAN (263-347): 2.41e-15: 78.9: 16.47