HitPredict

Interactor 1: ARF6 (P62330)
ADP-ribosylation factor 6 (EC 3.6.5.2)
Gene: ARF6

Interactor 2: COPG1 (Q9Y678)
Coatomer subunit gamma-1 (Gamma-1-coat protein) (Gamma-1-COP)
Gene: COPG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 175 Hs			1 874
+	Hs
		574783 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950585 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		950752 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		COPG1_HUMAN (1-874): 0: 859: 100.00
+	Hs
		574769 ARF4_HUMAN (1-173): 1.32e-70: 212: 64.74		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		950736 ARF5_HUMAN (2-173): 4.69e-69: 209: 65.12		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		913157 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Hs
		897411 ARF3_HUMAN (2-175): 4.91e-65: 198: 69.54		COPG2_HUMAN (1-874): 0: 837: 80.55
+	Dm
		778370 ARF4_DROME (1-173): 3.53e-69: 209: 65.32		COPG_DROME (11-874): 0: 719: 60.28
+	Dm
		897447 ARF1_DROME (2-175): 1.01e-64: 197: 70.12		COPG_DROME (11-874): 0: 719: 60.28
+	Hs
		950481 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Zm
		30041 B4FB55_MAIZE (10-174): 2.82e-66: 203: 18.82		A0A1D6K3D9_MAIZE (63-873): 0: 651: 14.29
+	Hs
		912875 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AP1B1_HUMAN (14-872): 0: 650: 13.46
+	Dm
		778364 ARF4_DROME (1-173): 3.53e-69: 209: 65.32		Q24253_DROME (14-872): 0: 629: 13.50
+	Dm
		897433 ARF1_DROME (2-175): 1.01e-64: 197: 70.12		Q24253_DROME (14-872): 0: 629: 13.50
+	Hs
		912839 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AP2B1_HUMAN (14-871): 0: 591: 12.40
+	Hs
		321520 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AP2A1_HUMAN (24-874): 0: 582: 14.63
+	Hs
		212618 ARF1_HUMAN (2-175): 4.43e-69: 209: 68.39		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52
+	Sc
		503061 ARF1_YEAST (2-175): 2.05e-68: 207: 66.09		COPG_YEAST (7-873): 7.79e-169: 516: 32.91
+	Hs
		212615 ARF6_HUMAN (1-175): 2.17e-65: 199: 100.00		AP1G1_HUMAN (17-741): 2.63e-170: 516: 15.52