HitPredict

Interactor 1: PRS10 (P62333)
26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene: PSMC6

Interactor 2: PRS10 (P62333)
26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene: PSMC6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 25416956, 28292943, 32296183, 15782218, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA_lid_3~AAA_lid_3, Prot_ATP_ID_OB~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 14 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 389
Hs

1 389
+ Hs
+ Hs
+ Dm
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024