HitPredict

Interactor 1: PRS10 (P62333)
26S proteasome regulatory subunit 10B (26S proteasome AAA-ATPase subunit RPT4) (Proteasome 26S subunit ATPase 6) (Proteasome subunit p42)
Gene: PSMC6

Interactor 2: ADRM1 (Q16186)
Proteasomal ubiquitin receptor ADRM1 (110 kDa cell membrane glycoprotein) (Gp110) (Adhesion-regulating molecule 1) (ARM-1) (Proteasome regulatory particle non-ATPase 13) (hRpn13) (Rpn13 homolog)
Gene: ADRM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 27114451
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 389 Hs			1 407
+	Hs
		906839 PRS4_HUMAN (14-380): 2.44e-135: 395: 41.42		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Hs
		907043 PRS8_HUMAN (5-387): 7.73e-122: 360: 47.00		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Hs
		66341 A8K2M0_HUMAN (3-383): 3.42e-121: 359: 40.68		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Hs
		798674 PRS6B_HUMAN (3-383): 3.42e-121: 359: 40.68		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Hs
		730270 PRS7_HUMAN (20-377): 3.86e-104: 315: 44.65		ADRM1_HUMAN (1-407): 8.77e-165: 470: 100.00
+	Dm
		1179242 Q9W414_DROME (5-389): 1.73e-131: 384: 89.35		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78
+	Dm
		186114 PRS8_DROME (5-387): 4.86e-126: 370: 47.00		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78
+	Dm
		1179225 Q9V405_DROME (6-383): 4.92e-120: 355: 40.74		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78
+	Dm
		1179214 Q7KMQ0_DROME (66-377): 2.33e-103: 313: 49.36		ADRM1_DROME (24-403): 1.81e-119: 354: 41.78