HitPredict

Interactor 1: E5RI47 (E5RI47)
MAGUK p55 scaffold protein 2
Gene: MPP2

Interactor 2: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	L27~L27, PDZ~PDZ
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Hs			1 233
+	Hs
		158282 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00
+	Hs
		158304 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00
+	Hs
		1050415 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17
+	Hs
		1050418 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38
+	Hs
		158254 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7A_HUMAN (1-233): 1.49e-59: 189: 100.00
+	Hs
		91352 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17
+	Hs
		1334778 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17
+	Hs
		91354 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38
+	Hs
		1346107 PALS2_HUMAN (1-189): 8.38e-71: 225: 64.80		LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38
+	Mm
		251089 CSKP_MOUSE (1-189): 5.18e-61: 205: 33.80		LIN7B_MOUSE (18-217): 8.75e-52: 168: 77.00
+	Hs
		159269 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17
+	Hs
		159277 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		LIN7C_HUMAN (18-211): 1.25e-50: 165: 79.38
+	Mm
		251090 CSKP_MOUSE (1-189): 5.18e-61: 205: 33.80		LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38
+	Mm
		1143555 MPP2_MOUSE (1-189): 9.84e-76: 238: 94.36		DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33
+	Hs
		1021489 MPP2_HUMAN (1-189): 1.3e-73: 233: 84.93		DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63
+	Hs
		91344 E5RI47_HUMAN (1-189): 2.48e-75: 226: 100.00		DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63
+	Hs
		159203 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		SNTB2_HUMAN (100-202): 5.76e-32: 123: 36.19
+	Hs
		159200 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63
+	Hs
		159190 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG4_HUMAN (5-232): 1.69e-24: 103: 18.33
+	Hs
		159249 CSKP_HUMAN (1-189): 5.08e-61: 205: 33.80		DLG3_HUMAN (22-179): 6.29e-20: 89.9: 21.34