HitPredict

Interactor 1: ABI2 (P62484)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Interactor 2: CYFP2 (Q5SQX6)
Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121)
Gene: Cyfip2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	28671696, 32560809
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Abi_HHR~FragX_IP
Common GO terms	GO:0031209 - SCAR complex
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 446 Mm			1 1253
+	Mm
		1131118 ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24		CYFP2_MOUSE (1-1253): 0: 2134: 100.00
+	Hs
		1224632 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		CYFP2_HUMAN (1-1253): 0: 2126: 97.97
+	Hs
		1290809 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		CYFP2_HUMAN (1-1253): 0: 2126: 97.97
+	Mm
		1186395 ABI1_MOUSE (1-446): 9.86e-108: 329: 61.24		CYFP1_MOUSE (1-1252): 0: 2041: 87.31
+	Hs
		1184628 ABI1_HUMAN (1-446): 3.25e-104: 320: 59.61		CYFP1_HUMAN (1-1252): 0: 2048: 87.55
+	Hs
		1184662 ABI2_HUMAN (1-446): 1.6e-93: 293: 79.92		CYFP1_HUMAN (1-1252): 0: 2048: 87.55
+	Mm
		561162 SPTN1_MOUSE (2-443): 9.46e-53: 193: 13.23		CYFP2_MOUSE (1-1253): 0: 2134: 100.00
+	Mm
		82761 B9EKJ1_MOUSE (2-443): 7.39e-53: 193: 13.23		CYFP2_MOUSE (1-1253): 0: 2134: 100.00
+	Mm
		1131060 SRC8_MOUSE (306-439): 1.36e-30: 125: 26.57		CYFP2_MOUSE (1-1253): 0: 2134: 100.00
+	Hs
		1290817 PACN2_HUMAN (291-441): 2.06e-28: 118: 25.00		CYFP2_HUMAN (1-1253): 0: 2126: 97.97
+	Mm
		561165 SPTN1_MOUSE (2-443): 9.46e-53: 193: 13.23		CYFP1_MOUSE (1-1252): 0: 2041: 87.31
+	Mm
		82765 B9EKJ1_MOUSE (2-443): 7.39e-53: 193: 13.23		CYFP1_MOUSE (1-1252): 0: 2041: 87.31
+	Hs
		1290813 ABI3_HUMAN (193-440): 4.18e-20: 93.3: 25.90		CYFP2_HUMAN (1-1253): 0: 2126: 97.97
+	Dm
		1365310 Q9Y0S9_DROME (1-442): 2.49e-75: 245: 37.85		CYFIP_DROME (1-1252): 0: 1908: 66.02