HitPredict

Interactor 1: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Interactor 2: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	9201987, 33961781, 26186194, 28514442, 24981860
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 67
+	Sp
		143452 RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42		RPAB5_SCHPO (1-67): 4.78e-33: 109: 71.64
+	Sc
		604669 RPB7_YEAST (1-171): 4.45e-63: 193: 42.78		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06
+	Hs
		921196 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPAB5_HUMAN (1-67): 3.73e-35: 114: 100.00
+	Sc
		604673 RPC8_YEAST (1-158): 1.07e-49: 160: 19.39		RPAB5_YEAST (1-67): 1.8e-30: 103: 72.06