HitPredict

Interactor 1: RPB7 (P62487)
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)
Gene: POLR2G

Interactor 2: RPR1B (Q9NQG5)
Regulation of nuclear pre-mRNA domain-containing protein 1B (Cell cycle-related and expression-elevated protein in tumor)
Gene: RPRD1B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 172 Hs			1 326
+	Hs
		913939 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		RPR1A_HUMAN (1-326): 1.47e-93: 282: 65.34
+	Hs
		913902 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		RPRD2_HUMAN (9-322): 2.87e-73: 247: 25.00
+	Hs
		1343471 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPR1B_HUMAN (1-326): 6.99e-94: 283: 100.00
+	Hs
		1299022 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPR1A_HUMAN (1-326): 1.47e-93: 282: 65.34
+	Hs
		1137978 RPC8_HUMAN (1-172): 5.28e-54: 171: 18.72		RPRD2_HUMAN (9-322): 2.87e-73: 247: 25.00
+	Hs
		304602 RPB7_HUMAN (1-172): 1.48e-76: 227: 100.00		SCAF4_HUMAN (8-187): 2.45e-36: 140: 17.46
+	Sp
		145822 RPB7_SCHPO (2-171): 1.24e-67: 205: 49.42		SEB1_SCHPO (1-206): 1.58e-33: 132: 14.41
+	Sc
		710025 RPB7_YEAST (1-171): 4.45e-63: 193: 42.78		NRD1_YEAST (7-211): 9.77e-29: 118: 12.99