HitPredict

Interactor 1: E7EN19 (E7EN19)
non-specific serine/threonine protein kinase (EC 2.7.11.1)
Gene: MAP4K4

Interactor 2: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1235 Hs			1 309
+	Hs
		324785 M4K4_HUMAN (1-1235): 0: 1088: 90.60		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		324775 M4K4_HUMAN (1-1235): 0: 1088: 90.60		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Mm
		915321 TNIK_MOUSE (1-1235): 0: 1081: 62.30		PP2AB_MOUSE (1-309): 0: 532: 100.00
+	Hs
		324752 M4K4_HUMAN (1-1235): 0: 1088: 90.60		PP1G_HUMAN (7-306): 0: 510: 46.60
+	Hs
		324770 M4K4_HUMAN (1-1235): 0: 1088: 90.60		PP1A_HUMAN (5-296): 0: 508: 47.18
+	Mm
		926532 TNIK_MOUSE (1-1235): 0: 1081: 62.30		PP1G_MOUSE (7-306): 0: 510: 46.60
+	Mm
		906234 TNIK_MOUSE (1-1235): 0: 1081: 62.30		PP1A_MOUSE (5-296): 0: 509: 47.51
+	Hs
		930991 SIK2_HUMAN (15-892): 1.01e-125: 412: 14.69		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		647866 MARK3_HUMAN (19-770): 5.11e-125: 405: 15.63		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Hs
		915261 MARK4_HUMAN (16-671): 7.66e-120: 391: 17.79		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Hs
		738035 SIK2_HUMAN (15-892): 1.01e-125: 412: 14.69		PP1G_HUMAN (7-306): 0: 510: 46.60
+	Hs
		906123 SIK2_HUMAN (15-892): 1.01e-125: 412: 14.69		PP1A_HUMAN (5-296): 0: 508: 47.18
+	Hs
		682162 AKT2_HUMAN (2-350): 2.88e-118: 377: 22.22		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		930913 M4K3_HUMAN (17-386): 1.52e-112: 375: 41.18		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		131564 STK25_HUMAN (14-445): 8.84e-116: 369: 35.32		PP2AA_HUMAN (1-309): 0: 533: 97.41
+	Hs
		131561 STK25_HUMAN (14-445): 8.84e-116: 369: 35.32		PP2AB_HUMAN (1-309): 0: 532: 100.00
+	Dm
		619909 Q9VEN3_DROME (20-340): 1.17e-114: 374: 42.72		PP2A_DROME (1-309): 0: 527: 94.50
+	Hs
		738092 MARK1_HUMAN (19-685): 8.17e-118: 387: 16.13		PP1G_HUMAN (7-306): 0: 510: 46.60
+	Dm
		619891 HIPPO_DROME (14-381): 2.05e-110: 363: 35.75		PP2A_DROME (1-309): 0: 527: 94.50
+	Hs
		131559 STK25_HUMAN (14-445): 8.84e-116: 369: 35.32		PP4C_HUMAN (4-309): 0: 511: 64.50