Interactor 1: HXK4 (P52792)
Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D)
Gene: Gck

Interactor 2: GCKR (Q91X44)
Glucokinase regulatory protein (GKRP) (Glucokinase regulator)
Gene: GCKR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 26620281
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains GKRP_SIS_2~Hexokinase_1, GKRP_SIS_2~Hexokinase_2
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 465
Mm

1 623
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025