HitPredict

Interactor 1: E7EPI0 (E7EPI0)
Inhibitor of Bruton tyrosine kinase
Gene: IBTK

Interactor 2: TTK (P33981)
Dual specificity protein kinase TTK (EC 2.7.12.1) (Phosphotyrosine picked threonine-protein kinase) (PYT)
Gene: TTK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Ank_2~Pkinase
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1338 Hs			1 857
+	Hs
		708376 IBTK_HUMAN (1-1338): 0: 1051: 98.89		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		1068514 IBTK_HUMAN (1-1338): 0: 1051: 98.89		KPCD1_HUMAN (176-857): 3.37e-133: 421: 15.27
+	Hs
		566495 IBTK_HUMAN (1-1338): 0: 1051: 98.89		KPCA_HUMAN (367-850): 2.8e-118: 375: 14.94
+	Hs
		1071710 IBTK_HUMAN (1-1338): 0: 1051: 98.89		KS6A2_HUMAN (525-818): 6.21e-81: 277: 22.29
+	Hs
		307244 RCBT2_HUMAN (377-925): 2.18e-44: 172: 13.82		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		708378 HERC5_HUMAN (127-355): 1.67e-42: 171: 24.48		TTK_HUMAN (1-857): 0: 776: 100.00
+	Hs
		1078069 HERC1_HUMAN (304-582): 3.33e-26: 120: 14.48		AKT3_HUMAN (468-857): 3.46e-119: 371: 18.05
+	Hs
		307257 RCBT2_HUMAN (377-925): 2.18e-44: 172: 13.82		ULK3_HUMAN (525-797): 3.59e-27: 117: 28.72