HitPredict

Interactor 1: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Interactor 2: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.944

The method score is based on:

Property Details
Experiments 25416956, 32296183, 11864604, 12180985, 14651967, unassigned1304
Identification Methods two hybrid, x-ray crystallography, pull down, far western blotting, unspecified method, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003707 - nuclear steroid receptor activity
GO:0004879 - nuclear receptor activity
and 12 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 458
Hs

1 458
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Last updated: 15 Jul 2024