HitPredict

Interactor 1: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Interactor 2: PNRC1 (Q12796)
Proline-rich nuclear receptor coactivator 1 (Proline-rich protein 2) (Protein B4-2)
Gene: PNRC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	15604093
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 458 Hs			1 327
+	Hs
		500363 RARB_HUMAN (34-455): 1.84e-121: 363: 28.37		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		782531 HNF4A_HUMAN (82-454): 3.83e-112: 340: 26.47		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		487957 RARA_HUMAN (62-455): 5.97e-112: 339: 28.92		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		530793 RARG_HUMAN (59-455): 2.33e-106: 324: 31.13		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		1016553 HNF4G_HUMAN (120-454): 5.91e-106: 322: 26.87		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		1016558 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		PNRC1_HUMAN (1-327): 0: 528: 100.00
+	Hs
		914676 ERR3_HUMAN (1-458): 1.22e-166: 478: 100.00		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		587199 RXRA_HUMAN (30-456): 6.83e-128: 380: 29.85		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		370500 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		782667 HNF4A_HUMAN (82-454): 3.83e-112: 340: 26.47		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		488025 RARA_HUMAN (62-455): 5.97e-112: 339: 28.92		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		510040 ERR1_HUMAN (38-456): 1.2e-109: 332: 55.32		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		530813 RARG_HUMAN (59-455): 2.33e-106: 324: 31.13		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		1055260 HNF4G_HUMAN (120-454): 5.91e-106: 322: 26.87		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32
+	Hs
		1269696 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		PNRC2_HUMAN (208-326): 3.46e-52: 170: 41.32