HitPredict

Interactor 1: ERR3 (P62508)
Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3)
Gene: ESRRG

Interactor 2: RAD50 (Q92878)
DNA repair protein RAD50 (hRAD50) (EC 3.6.-.-)
Gene: RAD50

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 458 Hs			1 1312
+	Hs
		370143 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00
+	Hs
		782613 HNF4A_HUMAN (82-454): 3.83e-112: 340: 26.47		RAD50_HUMAN (1-1312): 1.28e-115: 394: 100.00
+	Hs
		587127 RXRA_HUMAN (30-456): 6.83e-128: 380: 29.85		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		369096 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		377795 GCR_HUMAN (2-454): 6.64e-113: 351: 26.16		MYH2_HUMAN (556-1225): 9.34e-25: 114: 11.92
+	Hs
		368902 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		MYH6_HUMAN (524-1204): 1.26e-24: 114: 10.15
+	Hs
		370120 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		377326 GCR_HUMAN (2-454): 6.64e-113: 351: 26.16		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		369610 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		377068 GCR_HUMAN (2-454): 6.64e-113: 351: 26.16		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		368926 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		148263 ESR1_HUMAN (32-457): 2.07e-114: 350: 32.61		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		724944 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		MYH9_HUMAN (474-1226): 2.43e-26: 119: 10.19
+	Hs
		64608 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		MYH7B_HUMAN (416-1203): 3.03e-25: 116: 11.55
+	Hs
		522631 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		MYH7_HUMAN (524-1249): 1.05e-24: 114: 10.81
+	Hs
		1268061 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		MY18A_HUMAN (158-674): 1.53e-19: 97.7: 14.45
+	Hs
		1057341 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		SMC1A_HUMAN (290-1274): 4.82e-19: 95.7: 11.17
+	Hs
		551794 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		DESP_HUMAN (190-1069): 1.96e-10: 67.8: 18.71
+	Hs
		149132 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		CTRO_HUMAN (732-1116): 8.66e-10: 65.7: 12.15
+	Hs
		433179 ESR2_HUMAN (127-458): 1.2e-72: 239: 39.50		LAMB1_HUMAN (457-960): 2.73e-09: 63.9: 18.88