HitPredict

Interactor 1: YPEL5 (P62699)
Protein yippee-like 5
Gene: YPEL5

Interactor 2: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26186194, 28514442, 27173435, 29911972, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 391
+	Hs
		914882 YPEL5_HUMAN (1-121): 4.56e-60: 182: 100.00		RMD5B_HUMAN (1-391): 2.2e-152: 437: 69.72
+	Hs
		914869 YPEL5_HUMAN (1-121): 4.56e-60: 182: 100.00		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Sc
		746102 MOH1_YEAST (14-108): 7.54e-40: 131: 40.00		RMD5_YEAST (10-391): 2.85e-90: 280: 24.22
+	Hs
		914897 YPEL5_HUMAN (1-121): 4.56e-60: 182: 100.00		GID8_HUMAN (114-280): 5.61e-39: 141: 17.54
+	Dm
		1375221 YIPP_DROME (1-112): 2.38e-53: 165: 75.89		Q9VWS1_DROME (114-281): 3.32e-34: 128: 17.75
+	Sc
		746096 MOH1_YEAST (14-108): 7.54e-40: 131: 40.00		FYV10_YEAST (23-390): 1.01e-39: 149: 14.09
+	Hs
		914884 YPEL5_HUMAN (1-121): 4.56e-60: 182: 100.00		RANB9_HUMAN (87-214): 3.61e-11: 66.7: 16.41