HitPredict

Interactor 1: E7ESP4 (E7ESP4)
Integrin subunit alpha 2
Gene: ITGA2

Interactor 2: CD81 (P60033)
CD81 antigen (26 kDa cell surface protein TAPA-1) (Target of the antiproliferative antibody 1) (Tetraspanin-28) (Tspan-28) (CD antigen CD81)
Gene: CD81

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	32900848
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005178 - integrin binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 942 Hs			1 236
+	Hs
		566869 ITA2_HUMAN (1-942): 0: 1019: 100.00		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		566851 ITA2_HUMAN (1-942): 0: 1019: 100.00		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		566893 ITA2_HUMAN (1-942): 0: 1019: 100.00		TSN14_HUMAN (11-230): 6.42e-52: 170: 21.65
+	Hs
		326020 ITA2_HUMAN (1-942): 0: 1019: 100.00		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		880206 ITA1_HUMAN (1-940): 0: 950: 42.09		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		595498 ITAL_HUMAN (12-940): 0: 787: 27.63		CD82_HUMAN (4-234): 1.57e-49: 164: 23.11
+	Hs
		613229 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		CD81_HUMAN (1-236): 6.2e-63: 197: 100.00
+	Hs
		639879 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		613235 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		TSN5_HUMAN (7-235): 3.13e-55: 179: 21.67
+	Hs
		639875 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		50294 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		TSN11_HUMAN (10-232): 1.83e-54: 177: 26.86
+	Hs
		613224 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		CD151_HUMAN (3-231): 1.89e-54: 176: 25.40
+	Hs
		602219 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		602217 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		CD9_HUMAN (1-234): 3.88e-53: 172: 43.59
+	Hs
		639894 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		TSN14_HUMAN (11-230): 6.42e-52: 170: 21.65
+	Hs
		326269 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		TSN12_HUMAN (1-226): 5.72e-46: 156: 22.54
+	Hs
		156133 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		TSN4_HUMAN (5-236): 2.15e-45: 153: 25.73
+	Hs
		156132 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		TSN4_HUMAN (5-236): 2.15e-45: 153: 25.73
+	Hs
		326026 ITA3_HUMAN (2-443): 8.41e-63: 233: 16.34		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48
+	Hs
		326024 ITA6_HUMAN (14-508): 3.47e-62: 231: 16.57		TSN15_HUMAN (10-230): 9.93e-44: 150: 15.48