HitPredict

Interactor 1: PP2AB (P62714)
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) (EC 3.1.3.16)
Gene: PPP2CB

Interactor 2: STRN3 (Q13033)
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)
Gene: STRN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26496610, 33961781, 26186194, 28514442, 18782753, 35271311, 19156129
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 309 Hs			1 797
+	Hs
		930823 PP2AA_HUMAN (1-309): 0: 533: 97.41		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		215213 PP2AA_HUMAN (1-309): 0: 533: 97.41		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		215211 PP2AB_HUMAN (1-309): 0: 532: 100.00		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		931012 PP2AA_HUMAN (1-309): 0: 533: 97.41		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		915286 PP2AB_HUMAN (1-309): 0: 532: 100.00		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		930873 PP2AA_HUMAN (1-309): 0: 533: 97.41		Q59GV6_HUMAN (4-708): 1.62e-99: 327: 25.96
+	Hs
		915209 PP2AB_HUMAN (1-309): 0: 532: 100.00		Q59GV6_HUMAN (4-708): 1.62e-99: 327: 25.96
+	Hs
		108900 PP2AB_HUMAN (1-309): 0: 532: 100.00		H0YJT2_HUMAN (241-458): 4.34e-98: 303: 77.98
+	Dm
		87967 PP2A_DROME (1-309): 0: 527: 94.50		D3DML3_DROME (382-797): 1.67e-86: 292: 55.74
+	Hs
		737862 PP1G_HUMAN (7-306): 0: 510: 46.60		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Hs
		905965 PP1A_HUMAN (5-296): 0: 508: 47.18		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Hs
		108905 PP2AA_HUMAN (1-309): 0: 533: 97.41		H0YJZ4_HUMAN (283-458): 7.76e-77: 246: 78.41
+	Hs
		108904 PP2AB_HUMAN (1-309): 0: 532: 100.00		H0YJZ4_HUMAN (283-458): 7.76e-77: 246: 78.41
+	Mm
		292392 PP1A_MOUSE (5-296): 0: 509: 47.51		APAF_MOUSE (311-749): 2.3e-54: 206: 13.68
+	Hs
		737965 PP1G_HUMAN (7-306): 0: 510: 46.60		SNR40_HUMAN (525-796): 1.64e-14: 77.8: 23.76
+	Hs
		906069 PP1A_HUMAN (5-296): 0: 508: 47.18		SNR40_HUMAN (525-796): 1.64e-14: 77.8: 23.76
+	Zm
		32619 A0A1D6KVM0_MAIZE (48-309): 2.45e-179: 501: 84.35		B6T9K7_MAIZE (191-470): 2.63e-16: 82.5: 9.03