Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: ACTS (P68133)
Actin, alpha skeletal muscle (EC 3.6.4.-) (Alpha-actin-1) [Cleaved into: Actin, alpha skeletal muscle, intermediate form]
Gene: ACTA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~Actin
Common GO terms GO:0001725 - stress fiber
GO:0005524 - ATP binding
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0010628 - positive regulation of gene expression
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 377
Hs

1 377
+ Hs
+ Hs
+ Hs
+ Sp
+ Dm
+ Dm
+ Dm
+ Dm
+ At
+ Ce
+ Ce
+ Ce
+ Ce
+ Ce
+ Oc
+ Gg
+ Gg
+ Hs

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Last updated: 15 Jul 2024