HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: OCRL (Q01968)
Inositol polyphosphate 5-phosphatase OCRL (EC 3.1.3.36) (EC 3.1.3.56) (Inositol polyphosphate 5-phosphatase OCRL-1) (OCRL-1) (Lowe oculocerebrorenal syndrome protein) (Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase) (EC 3.1.3.86)
Gene: OCRL

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	25107275
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Actin~RhoGAP
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 901
+	Hs
		968157 ACTBL_HUMAN (4-377): 0: 712: 87.97		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		891704 ACTB_HUMAN (4-377): 0: 598: 94.12		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		929827 ACTG_HUMAN (4-377): 0: 598: 94.39		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		932111 ACTC_HUMAN (1-377): 0: 598: 98.41		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		932957 ACTS_HUMAN (1-377): 0: 598: 97.88		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Hs
		930080 ACTH_HUMAN (4-377): 0: 591: 99.20		OCRL_HUMAN (1-901): 0: 1075: 100.00
+	Sc
		842744 ACT_YEAST (4-377): 0: 643: 86.63		INP52_YEAST (215-740): 1.66e-123: 404: 27.00
+	Hs
		203220 ACTC_HUMAN (1-377): 0: 598: 98.41		SYNJ1_HUMAN (218-733): 8.18e-121: 403: 24.37