HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: DAPLE (Q9P219)
Protein Daple (Coiled-coil domain-containing protein 88C) (Dvl-associating protein with a high frequency of leucine residues) (hDaple) (Hook-related protein 2) (HkRP2)
Gene: CCDC88C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 2028
+	Hs
		724859 ACTBL_HUMAN (4-377): 0: 712: 87.97		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Dm
		115212 ACT1_DROME (1-377): 0: 597: 93.90		M9PEG0_DROME (525-1416): 3.84e-40: 165: 18.55
+	Hs
		932162 ACTC_HUMAN (1-377): 0: 598: 98.41		NUMA1_HUMAN (2-1111): 1.36e-36: 154: 11.67
+	Hs
		892003 ACTB_HUMAN (4-377): 0: 598: 94.12		CP250_HUMAN (613-1708): 8.43e-35: 149: 11.02
+	Hs
		725136 ACTC_HUMAN (1-377): 0: 598: 98.41		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Hs
		725135 ACTH_HUMAN (4-377): 0: 591: 99.20		MYH10_HUMAN (871-1748): 1.31e-32: 141: 11.80
+	Mm
		892205 ACTB_MOUSE (4-377): 0: 598: 94.12		MYH9_MOUSE (993-1831): 1.44e-28: 128: 10.44
+	Rn
		892236 ACTB_RAT (4-377): 0: 598: 94.12		MYH10_RAT (950-1831): 3.59e-28: 127: 10.06
+	Rn
		892228 ACTB_RAT (4-377): 0: 598: 94.12		MYH9_RAT (1054-1851): 2.69e-25: 117: 11.15
+	Hs
		929915 ACTG_HUMAN (4-377): 0: 598: 94.39		HOOK3_HUMAN (4-548): 2.59e-25: 116: 24.56
+	Hs
		148662 ACTC_HUMAN (1-377): 0: 598: 98.41		CTRO_HUMAN (857-1394): 2.99e-24: 114: 14.39
+	Hs
		724738 ACTB_HUMAN (4-377): 0: 598: 94.12		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		724762 ACTG_HUMAN (4-377): 0: 598: 94.39		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		724766 ACTC_HUMAN (1-377): 0: 598: 98.41		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		724767 ACTS_HUMAN (1-377): 0: 598: 97.88		MYH9_HUMAN (1121-1764): 4.43e-21: 103: 12.65
+	Hs
		891686 ACTB_HUMAN (4-377): 0: 598: 94.12		MAP1A_HUMAN (228-541): 1.95e-10: 68.5: 12.54
+	Hs
		828573 ACTC_HUMAN (1-377): 0: 598: 98.41		CENPF_HUMAN (488-1376): 4.85e-10: 67.4: 20.72